中山大学学报（医学科学版）2018，Vol.39Issue(3)：472-476,5.
超声引导肉毒毒素注射治疗环咽肌功能障碍探讨
Therapeutic Effects of Ultrasound-Guided Injection of Botulinum Toxin Type A into the Cricopharyngeus Muscle for Cricopharyngeal Dysfunction
林晓婷 1杨海云 2栗晓 1伍少玲 1马超1
作者信息
- 1. 中山大学孙逸仙纪念医院康复医学科,广东广州510120
- 2. 中山大学孙逸仙纪念医院超声科,广东广州510120
- 折叠
摘要
Abstract
[Objective] To investigate the feasibility and effectiveness of using ultrasound-guided cricopharyngeal (CP) botulinum toxin (BTX) injection to treat cricopharyngeal dysfunction after brainstem infarction.[Method] A patient with dysphagia caused by subacute lacunar infarction in the right pontobulbar junction was diagnosed with incomplete opening of cricopharyngeal muscle by videofluoroscopic swallowing study (VFSS).After precisely locating the CP muscle with catheter balloon and ultrasound,we injected BTX (25 U/0.8 mL) into the left CP muscle using the out-of-plane approach technique.[Result] After the injection,the patient made great progress in swallowing.He was able to eat porridge independently without bucking on the 5th day,while soft rice on the 8th day and sip water.Two weeks after the injection,VFSS showed that the bolus progressed into the esophagus fluently without the route getting narrow or broken off,and hardly found residue in pharynx,which suggested that the CP muscle could open properly.[Conclusion] Cricopharyngeal injection of BTX guided by ultrasound is a safe and effective way to treat cricopharyngeal dysfunction after brainstem infarction,which is also convenient to operate and deserves to be disseminated after the further studies proves its effectiveness.关键词
环咽肌功能障碍/吞咽困难/超声引导/肉毒毒素注射Key words
cricopharyngeal dysfunction/dysphagia/ultrasound-guided/botulinum toxin (BTX) injection分类
医药卫生引用本文复制引用
林晓婷,杨海云,栗晓,伍少玲,马超..超声引导肉毒毒素注射治疗环咽肌功能障碍探讨[J].中山大学学报（医学科学版）,2018,39(3):472-476,5.
