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响应面法优化天麻多糖的超声提取工艺

马彦江 于兰兰 刘瑞霞 陈天朝

中国现代中药2018,Vol.20Issue(5):599-603,5.
中国现代中药2018,Vol.20Issue(5):599-603,5.DOI:10.13313/j.issn.1673-4890.20170901001

响应面法优化天麻多糖的超声提取工艺

Optimization of Ultrasonic Extraction Process of Gastrodia elata using Response Surface Methodology

马彦江 1于兰兰 2刘瑞霞 3陈天朝4

作者信息

  • 1. 河南中医药大学第一附属医院药学部,河南 郑州 450000
  • 2. 河南中医药大学第一附属医院省级中药炮制技术传承基地,河南 郑州 450000
  • 3. 河南省直第三人民医院药剂科,河南 郑州 450006
  • 4. 中牟县中医院药剂科,河南 中牟 451450
  • 折叠

摘要

Abstract

Objective:To optimize the extraction process of polysaccharides from Gastrodia elata by response surface analysis.Methods:The method of response surface methodology with 3 factors and 3 levels was adopted on optimizing the ul-trasonic extraction technology of G.elata polysaccharides. Three response factors were the fixed extraction temperature,extrac-tion time and liquid-solid ratio and the experimental yield of polysaccharides as the response value.Results:The optimal ex-traction conditions of polysaccharides were determined as follows:extraction temperature 78.54 ℃,extraction time 48.06 min,liquid-solid ratio of 16.04:1.Under these conditions,the experimental yield of polysaccharides was agreed closely with the predicted value(17.25%).Conclusion:The experimental yield of polysaccharides was agreed closely with the predic-ted value,which means it was feasible to optimize extraction process of polysaccharides from G.elata by response surface anal-ysis methodology.

关键词

响应面法/天麻多糖/提取工艺

Key words

Response surface methodology/Gastrodia elata polysaccharide/extraction process

引用本文复制引用

马彦江,于兰兰,刘瑞霞,陈天朝..响应面法优化天麻多糖的超声提取工艺[J].中国现代中药,2018,20(5):599-603,5.

基金项目

河南省科技发展计划项目(142102310278) (142102310278)

中国现代中药

OACSTPCD

1673-4890

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