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正交试验法优选益肾涤浊丸提取工艺

彭爱娜 杨珊 田素英

中国现代中药2018,Vol.20Issue(5):609-612,4.
中国现代中药2018,Vol.20Issue(5):609-612,4.DOI:10.13313/j.issn.1673-4890.20171110005

正交试验法优选益肾涤浊丸提取工艺

Optimization of Extraction Process of Yishen Dizhuo Pills by Orthogonal Experiment

彭爱娜 1杨珊 2田素英2

作者信息

  • 1. 广东省肇庆市中医院,广东 肇庆 526060
  • 2. 广东药科大学,广东 广州 510006
  • 折叠

摘要

Abstract

Objective:To optimize the extraction process of Yishen Dizhuo Pills by orthogonal design test.Methods:The effect of solid-liquid ratio,soak and extract time,extracting times,ethanol concentration on the yield of extract and the content of berberine hydrochloride extraction process of Yishen Dizhuo Pills was investigated,and the extraction process was optimized by L9(34)orthogonal test.Results:The optimized process on water-extract:solid-liquid ratio was 1:10,soak period was 60 minute,extraction time was 1.5 hour,extraction times was 3.The optimized process on ethanol extraction:solid-liquid ratio was 1:10,ethanol concentration was 50%,the extraction time was 2 hour,and extraction times was 3.Conclusion:The optimized process is feasible,rational and the extraction rate of active components is optimal,which can be applied to the Yishen Dizhuo Pills extraction process.

关键词

益肾涤浊丸/正交试验/水提药材/醇提药渣/提取工艺

Key words

Yishen Dizhuo Pill/orthogonal design test/water extraction/ethanol extraction/extraction process

引用本文复制引用

彭爱娜,杨珊,田素英..正交试验法优选益肾涤浊丸提取工艺[J].中国现代中药,2018,20(5):609-612,4.

基金项目

益肾涤浊丸的制备工艺研究(2016040304) (2016040304)

中国现代中药

OACSTPCD

1673-4890

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