北京中医药大学学报2018，Vol.41Issue(5)：395-399,5.DOI:10.3969/j.issn.1006-2157.2018.05.007
以类平均聚类法分析不同产地土贝母中土贝母苷甲含量及影响因素
Content and influencing factors of tobeimoside I in Tubeimu from different producing areas analyzed by using group-average clustering method
摘要
Abstract
Objective To identify the content of tubeimoside I in Paniculate Bolbostemma from 16 differ-ent locations and determine the high-containing locations and influencing factors.Methods The quanti-tative determination method of tobeimoside I in Tubeimu(Paniculate Bolbostemma, Rhizoma Bolbostem-atis)in Chinese Pharmacopoeia(2015 Edition)was used to determine the content of tobeimoside I in 16 batches of Tubeimu for deciding producing areas with higher content of Tubeimu and analyzing the influ-encing factors.The origin producing areas was classified by using group-average clustering analysis meth-od taken content of tobeimoside I as the index.Results The results showed that the content of tobeimo-side I was in a range from 1.234%to 3.174%in different producing areas,which was accorded with the requirement of Chinese Pharmacopoeia.The clustering analysis classified 16 producing areas into 4 groups,and content of tobeimoside I was the highest in Tubeimu material produced from Shangluo and Hanzhong.Conclusion The temperature and humidity had influence on Tubeimu material, and content of tobeimoside I was higher in the producing areas with higher temperature and humidity.关键词
土贝母/土贝母苷甲/类平均法/聚类分析Key words
Tubeimu(Paniculate Bolbostemma/Rhizoma Bolbostematis)/tobeimoside I in Tubeimu/group-average method/clustering analysis分类
医药卫生引用本文复制引用
谭宁,陆洋,薛宇涛,李彦萍,曾滟棱,杜守颖..以类平均聚类法分析不同产地土贝母中土贝母苷甲含量及影响因素[J].北京中医药大学学报,2018,41(5):395-399,5.基金项目
科技部重大科技专项"重大新药创制"资助项目(No.2014ZX09301306-008),北京市科技新星计划资助项目(No.XX2015A048)National Major Scientific and Technological Special Project for"Significant New Drugs Development"of China(No.2014ZX09301306-008),Bei-jing New-star Plan of Science and Technology(No.XX2015A048) （No.2014ZX09301306-008）
