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期待与清宫治疗中期引产后宫内妊娠物残留的预后及并发症

曾文娟 安胜利 黄浩 黄启涛 李飞凤 王海臻 蔡丹纯 高云飞

南方医科大学学报2017,Vol.37Issue(5):569-574,6.
南方医科大学学报2017,Vol.37Issue(5):569-574,6.DOI:10.3969/j.issn.1673-4254.2017.05.01

期待与清宫治疗中期引产后宫内妊娠物残留的预后及并发症

Expectant therapy versus curettage for retained products of conception after second trimester termination of pregnancy:analysis of outcomes and complications

曾文娟 1安胜利 2黄浩 3黄启涛 1李飞凤 1王海臻 1蔡丹纯 1高云飞1

作者信息

  • 1. 南方医科大学南方医科妇产科,广东广州510515
  • 2. 南方医科大学公共卫生学院生物统计学系,广东广州510515
  • 3. 耶鲁大学公共卫生学院生物统计学系,美国 纽黑文
  • 折叠

摘要

Abstract

Objective To evaluate the prognosis and complications of expectant therapy and curettage for retained product of conception (RPOC) after second trimester termination of pregnancy (TOP).Methods A total of 270 patients with RPOC following second trimester TOP in Nanfang Hospital between January,2014 and December,2015 were included in this study.The duration of vaginal bleeding time and menstruation recovery interval were compared between patients receiving expectant therapy and curettage for RPOC,and binary logistic regression was used to assess the risk factors for complications in bivariate and multivariate analyses.Results The duration of vaginal bleeding time was significantly longer in expectant therapy group than in curettage group (P=0.005),while the menstruation recovery interval did not differ significantly between the two groups.The incidence of vaginal bleeding time for over 42 days was significantly higher in curettage group than in expectant therapy group (P=0.040),and the incidence of a menstruation recovery interval beyond 60 days was comparable between them.The incidence of complications was significantly higher in curettage group than in expectant therapy group either with adjustment of age,gravidity,parity,history of uterine surgery status,gestational age,type of indications,regimens for TOP and induction-abortion interval (OR=18.26 [95% CI:3.57-93.42],P<0.001) or without adjustment (OR=10.60,[95% CI:2.36-47.66],P=0.002).Conclusion Expectant therapy and curettage for RPOC after second trimester TOP have comparable prognosis,but curettage is associated with a significantly higher rate of complications.

关键词

中期引产/宫内妊娠物残留/清宫/期待治疗/预后/并发症

Key words

termination,pregnancy/retained product of conception/curettage/expectant therapy/prognosis/complication

引用本文复制引用

曾文娟,安胜利,黄浩,黄启涛,李飞凤,王海臻,蔡丹纯,高云飞..期待与清宫治疗中期引产后宫内妊娠物残留的预后及并发症[J].南方医科大学学报,2017,37(5):569-574,6.

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1673-4254

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