南方医科大学学报2017，Vol.37Issue(5)：693-697,5.DOI:10.3969/j.issn.1673-4254.2017.05.22
手术治疗低体质量指数2型糖尿病患者的临床疗效
Efficacy of two bariatric surgeries in type 2 diabetic patients with a body mass index of 25-27.5
摘要
Abstract
Objective To evaluate the therapeutic effects of laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic duodenal-jejunal bypass with sleeve gastrectomy (SADJB-SG) in patients with type 2 diabetes mellitus and a low body mass index (BMI) of 25-27.5.Methods Thirty-one type 2 diabetic patients with a BMI of 25-27.5 underwent bariatric surgeries in the General Hospital of Guangzhou Military Command between August,2013 and August,2015.The patients receiving LRYGB (17 cases) and SADJB-SG (14 cases) were compared for physical indexes,glucose metabolism and of pancreatic islet function at 1 year after the surgeries.Results No mortality occurred in the patients after the operations.At 1 year after the operation,the patients in LRYGB group showed significant improvements in body weight,BMI,glycated hemoglobin (HbA1c),fasting plasma glucose (FPG),oral glucose tolerance test 2 h (OGTT2h),C-peptide,fasting insulin (FINS),and postprandial 2 hour insulin (2 hPINS) (P＜0.05);in SADJB-SG group,significant improvements were observed in the body weigh,BMI,HbA1c,FPG,OGTT2h,and FINS after the operation (P＜0.05).The postoperative improvements in body weigh,BMI,HbA1c,FPG,OGTT2h,C-peptide,and 2hPINS were comparable between SADJB-SG group and LRYGB group (P＞0.05),but the incidence of postoperative anastomotic ulcer was lower in SADJB-SG group.Conclusion SADJB-SG and LRYGB produce similar therapeutic effects in type 2 diabetic patients with a low BMI,but SADJB-SG is associated with a low incidence of postoperative complications and is therefore more suitable in such patients.关键词
2型糖尿病/减重代谢外科/胃旁路术/袖状胃切除十二指肠空肠旁路术Key words
type 2 diabetes mellitus/bariatric and metabolic surgery/laparoscopic Roux-en-Y gastric bypass/laparoscopic single-anastomosis duodenal-jejunal bypass with sleeve gastrectomy引用本文复制引用
余浩,戴晓江,张红兵,黄永滔,冉冬芝,杨园,曾松华,宋志高,吴良平..手术治疗低体质量指数2型糖尿病患者的临床疗效[J].南方医科大学学报,2017,37(5):693-697,5.基金项目
广州市科技计划项目(201508020002) （201508020002）
