国际医学放射学杂志2018，Vol.41Issue(3)：290-293,4.DOI:10.19300/j.2017.L5589
症状性缺血性脑卒中颈动脉斑块成分的高分辨MRI分析
Carotid plaque components assessment by high-resolution MRI in patients with symptomatic ischemic stroke
崔振杰 1王巍 1张原理 1姜慧杰 1刘鹏飞1
作者信息
- 1. 哈尔滨医科大学附属第一医院放射科,哈尔滨150001
- 折叠
摘要
Abstract
Objective To study the risk of different components of carotid plaque in patients with symptomatic ischemic stroke by using high resolution magnetic resonance imaging(HRMRI).Methods Fifty cases with carotid plaques were screened by ultrasound examination from January 2016 to June 2017.Among these patients,21 women and 29 men,age range 43~77 years old,average 61.62±7.96 years.Depending on whether presence of symptoms which were associated with corresponding carotid artery during the last 3 months,the patients were divided into the symptomatic group(22 cases,number of arteries with plaques=40)and the asymptomatic group(28 cases,number of arteries with plaques=50).The 3.0 T HRMRI was used to evaluate the carotid artery blood vessel and plaque compositions for all patients. The clinical data, plaque compositions,and the degree of vascular stenosis of the 2 groups were compared by t test or Chi-square test.The independent risk factors of ischemic symptoms were analyzed by logistic regression.Results The fibrous cap rupture(FCR)of plaque was detected in 15 arteries(37.5%)in the symptom group,in 8 arteries(16.0%)in the asymptomatic group.The incidence of FCR(37.5% vs. 16.0%; P<0.05)was significantly higher in the symptomatic than asymptomatic patients. Intraplaque hemorrhage(IPH)was detected in 21 arteries(52.5%)in the symptomatic group;in 15 arteries(30.0%)in the asymptomatic group,, the IPH in the symptomatic group was significantly more than that in the asymptomatic group(P<0.05). Plaque calcification was detected in 15 arteries(37.5%)in the symptom group,in 13 arteries(26.0%)in the asymptomatic group.The difference between the two groups was not statistically significant(P>0.05).The degree of vascular stenosis was 57.64%±13.36% in the symptomatic group and 53.86% ±11.19% in the asymptomatic group,The difference between the two groups was not statistically significant(P=0.148).The multivariate analysis of logistic regression model showed that FCR had the highest risk of symptomatic ischemic stroke(OR=3.012),and followed by IPH(OR=2.478).Conclusion HRMRI can effectively identify plaque compositions,and can evaluate the risk factors for the occurrence of clinical symptoms in ischemic stroke and plaque vulnerability.关键词
颈动脉/粥样硬化斑块/缺血性脑卒中/磁共振成像Key words
Carotid artery/Atherosclerotic plaque/Ischemic stroke/Magnetic resonance imaging分类
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崔振杰,王巍,张原理,姜慧杰,刘鹏飞..症状性缺血性脑卒中颈动脉斑块成分的高分辨MRI分析[J].国际医学放射学杂志,2018,41(3):290-293,4.
