神经损伤与功能重建2018，Vol.13Issue(5)：225-227,3.DOI:10.16780/j.cnki.sjssgncj.2018.05.003
不同病因下急性脑梗死合并缺血性脑白质病变与血同型半胱氨酸水平的相关性探讨
Study on the Correlation Between ACI Combining with Ischemic Leukodystrophy and Homocysteine Level Under Different Disease Causes
摘要
Abstract
Objective: To discuss the correlation between homocysteine (Hcy) level and acute cerebral infarction (ACI) combining with white matter ischemic lesion (WMIL) under different disease causes. Methods:A total of 280 patients with ACI combined with WMIL verified by CT and MRI were recruited to this study.Patients were divided into the atherosclerosis thrombotic cerebral infarction only group(AT group),WMIL only group(WMIL group),(AT+WMIL)group,and(SAO+WMIL)group,with 70 patients per group.The level of Hcy was measured for comparisons among groups. Results:The Hcy level of the (AT+WMIL) group and (SAO+WMIL) group was higher than that of the WMIL group (P<0.05,P<0.05). Logistic regression analysis indicated that age and TG are statistically significant factors in ACI patients with WMIL(P<0.05);meanwhile, Hcy showed more statistical significance in these patients(P<0.01).Conclusion:Elevated Hcy level is closely related to ACI with WMIL,but it has no correlation with the etiology of ACI with WMIL.关键词
缺血性脑白质病变/脑梗死/同型半胱氨酸/改良TOAST分型Key words
ischemic leukodystrophy/cerebral infarction/blood homocysteine/modified TOAST classification分类
医药卫生引用本文复制引用
涂宇,巩萱,卓文燕,陈欢,林晶,范玉华..不同病因下急性脑梗死合并缺血性脑白质病变与血同型半胱氨酸水平的相关性探讨[J].神经损伤与功能重建,2018,13(5):225-227,3.基金项目
国家自然科学基金(No.81000514) （No.81000514）
广东省自然科学基金(No.S2013010015840) （No.S2013010015840）
