摘要
Abstract
Objective To investigate the effect of phacoemulsification(PHACO) combined with intraocular lens(IOL) implantation on the corneal endothelium in patients with diabetic cataract(DC).Methods One hundred and sixty-three patients with cataract were enrolled,including 74 cases of DC (diabetic group) and 89 cases of simple senile cataract(control group),and all patients underwent PHACO combined with IOL implantation.Corneal endothelial microscope was used to detect the central corneal density(CCD) of endothelial cell,coefficient of variation(CV),percentage of hexagonal cells(6A%),average area of endothelial cell(AVE),and central corneal thickness in the two groups before and after one and three months of operation.Results At each time point after operation,both CCD and 6A% in the diabetic group were lower than those in the control group,after one month of operation,AVE in the diabetic group was higher than that in the control group(all P<0.05).In both groups,CCD and 6A% decreased first and then increased,while AVE increased first and then decreased (all P<0.05).Conclusion PHACO combined with IOL implantation has damage to corneal endothelial cells to a certain extent.Patients with DC suffer from severer damage to corneal endothelial cells compared to patients with simple senile cataract.However,the damage to corneal endothelial cells presents a tendency to reduce over time.关键词
白内障/糖尿病/超声乳化/人工晶状体/角膜内皮Key words
Cataract/diabetes mellitus/Phacoemulsification/Intraocular lens/Corneal endothelium分类
医药卫生
