基础医学与临床2018,Vol.38Issue(6):849-852,4.
外泌体治疗脊髓损伤的研究进展
Research progress of exosomes in treating spinal cord injury
摘要
Abstract
Exosomes are membrane vesicles secreted by cells into the extracellular environment. Exosomes are a new cell component in the treatment of spinal cord injury. Exosomes are secreted by mesenchymal stem cells have anti-apoptotic, anti-inflammatory and pro-angiogenic effects in the treatment of spinal cord injury, which play a key role in nerve cell-cell communication and can delivery exogenous genetic material. Exosomes can penetrate blood-brain barrier and are more stable than their parent cells, reducing the safety risks in the administration of viable cells.关键词
脊髓损伤/外泌体/间充质干细胞Key words
spinal cord injury/exosomes/mesenchymal stem cells分类
医药卫生引用本文复制引用
史冬玲,何冰倩,戴灵豪..外泌体治疗脊髓损伤的研究进展[J].基础医学与临床,2018,38(6):849-852,4.基金项目
浙江中医药大学校级科研基金(2017ZY20) (2017ZY20)
浙江省教育厅科研项目(Y201636861) (Y201636861)