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外泌体治疗脊髓损伤的研究进展

史冬玲 何冰倩 戴灵豪

基础医学与临床2018,Vol.38Issue(6):849-852,4.
基础医学与临床2018,Vol.38Issue(6):849-852,4.

外泌体治疗脊髓损伤的研究进展

Research progress of exosomes in treating spinal cord injury

史冬玲 1何冰倩 1戴灵豪1

作者信息

  • 1. 浙江中医药大学 中医药科学院,浙江 杭州311400
  • 折叠

摘要

Abstract

Exosomes are membrane vesicles secreted by cells into the extracellular environment. Exosomes are a new cell component in the treatment of spinal cord injury. Exosomes are secreted by mesenchymal stem cells have anti-apoptotic, anti-inflammatory and pro-angiogenic effects in the treatment of spinal cord injury, which play a key role in nerve cell-cell communication and can delivery exogenous genetic material. Exosomes can penetrate blood-brain barrier and are more stable than their parent cells, reducing the safety risks in the administration of viable cells.

关键词

脊髓损伤/外泌体/间充质干细胞

Key words

spinal cord injury/exosomes/mesenchymal stem cells

分类

医药卫生

引用本文复制引用

史冬玲,何冰倩,戴灵豪..外泌体治疗脊髓损伤的研究进展[J].基础医学与临床,2018,38(6):849-852,4.

基金项目

浙江中医药大学校级科研基金(2017ZY20) (2017ZY20)

浙江省教育厅科研项目(Y201636861) (Y201636861)

基础医学与临床

OACSCDCSTPCD

1001-6325

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