兰州大学学报（医学版）2017，Vol.43Issue(1)：31-35,5.DOI:10.13885/j.issn.1000-2812.2017.01.006
桥本氏甲状腺炎合并甲状腺癌的临床及病理研究
Clinical and pathological features of Hashimoto's thyroiditis complicated with thyroid cancer
张德杰 1林国樑 1张铭 1张迪添 1廖铭兴 1王启才 1杨先荣1
作者信息
- 1. 福建医科大学附属龙岩第一医院 普三科,福建龙岩364000
- 折叠
摘要
Abstract
Objective To compare the features of purely thyroid cancer and thyroid cancer complicated with Hashimoto's thyroiditis.Methods Chose the thyroid cancer patients who were diagnosed by pathology from January 2012 to December 2015,and then divided the 317 patients into experimental group that was complicated with Hashimoto's thyroiditis and control group that was not,and then compared the ultrasonic,pathological and clinical features of two groups.Results Compared with the control group,the experimental group was much younger (P ＜ 0.05) and had a higher female ratio (P ＜ 0.05).In terms of thyroid functionality,the TGAb,TPOAb and TSH level of the experimental group were higher than the control group (P ＜ 0.05).In terms of accuracy of ultrasound,lesions of the experimental group had more calcification (P ＜ 0.05),but not rich in blood supply (P ＜ 0.05).The accuracy of ultrasound predictions at cervical lymph node metastasis showed no difference between the two groups (P ＞ 0.05).In terms of postoperative pathological features,the proportion of papillary thyroid cancer of the experimental group was higher than the control group (P ＞ 0.05).The average size of the experimental group (1.67±0.44cm) was smaller than the control group (1.91±0.69cm)(P ＜ 0.05).The proportion of papillary microcarcinoma of the thyroid of the experimental group (18/47) was higher than the control group (42/270)(P ＜ 0.05),and the proportion of multi-centers of the experimental group (19/47) was higher than control group (61/270) too (P ＜ 0.05).The chances of cervical lymph node metastasis of the experimental group (17/47) was smaller than the control group (151/270) (P ＜ 0.05),and the ratio of capsule invasion of the experimental group (7/47) was lower than the control group (84/270) too (P ＜ 0.05).Conclusion Thyroid cancer complicated with Hashimoto' s thyroiditis is different from thyroid cancer without the complication,and these patients might have a better prognosis,relatively speaking,and further research into the intrinsic mechanism may useful to the treatment of different characteristics and different types of thyroid cancer.关键词
桥本氏甲状腺炎/甲状腺癌/甲状腺乳头状癌Key words
Hashimoto's thyroiditis/thyroid cancer/papillary thyroid cancer分类
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张德杰,林国樑,张铭,张迪添,廖铭兴,王启才,杨先荣..桥本氏甲状腺炎合并甲状腺癌的临床及病理研究[J].兰州大学学报（医学版）,2017,43(1):31-35,5.
