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不同跑台坡度对SD大鼠运动疲劳指标的影响

石鹤坤 陈开杰 林小凤 禹乐 朱启淦 费燕

实验动物与比较医学2017,Vol.37Issue(6):455-459,5.
实验动物与比较医学2017,Vol.37Issue(6):455-459,5.DOI:10.3969/j.issn.1674-5817.2017.06.006

不同跑台坡度对SD大鼠运动疲劳指标的影响

Effect of Different Treadmill Slope on Exercise Fatigue Index in SD Rats

石鹤坤 1陈开杰 1林小凤 1禹乐 2朱启淦 2费燕1

作者信息

  • 1. 解放军第175医院/厦门大学附属东南医院药学科,漳州363000
  • 2. 解放军第175医院/厦门大学附属东南医院病理科,漳州363000
  • 折叠

摘要

Abstract

Objective To study the influence of exercise fatigue index on different treadmill slope in rats.Methods 32 SD rats were randomly divided into 4 groups:the control group,and 0°-,-15°-and.15 °-treadmill slope exercise groups.The model group was given treadmill exercise according to the scheme.Related indexes were detected after 6 weeks training.The serum content of glucose(GLU),blood urea nitrogen(BUN),lactic acid (LA),creatine kinase (CK),hemoglobin (HGB),red blood cell (RBC).Gastrocnemius muscle index and the number of electric shock in the rats were calculated.Results Compared with the control group,there were significant changes in the blood metabolites,energy material and exercise ability during different treadmill slope exercise in the rats.The GLU,HGB and RBC in the peripheral blood samples of each exercise group were significantly lower than those in the control group (P<0.01,P<0.05),and the gastrocnemius muscle index was significantly higher (P<0.01).The serum of LA,BUN concentration and CK activity were significantly increased (P<0.01,P<0.05) in the 15° treadmill and-15° treadmill exercise groups.Compared with the 0° treadmill exercise group,the number of electric shock in the rats were significantly increased in the 15 ° treadmill and-15 ° treadmill exercise groups (P<0.05).HE staining showed that the gastrocnemius muscle cells of rats had a tendency of swelling and injury after exercise.Conclusions At 15 ° treadmill exercise groups,the exercise fatigue model replication of rats was better than that of 0° or-15 ° treadmill exercise groups.

关键词

运动疲劳模型/跑台坡度/运动能力/大鼠

Key words

Exercise-induced fatigue/Treadmill slope/Exercise ability/Rat

分类

生物科学

引用本文复制引用

石鹤坤,陈开杰,林小凤,禹乐,朱启淦,费燕..不同跑台坡度对SD大鼠运动疲劳指标的影响[J].实验动物与比较医学,2017,37(6):455-459,5.

基金项目

解放军第175医院青年苗圃基金资助项目(No.13Y017) (No.13Y017)

实验动物与比较医学

OACSTPCD

1674-5817

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