中国比较医学杂志2018，Vol.28Issue(5)：70-74,5.DOI:10.3969/j.issn.1671-7856.2018.05.013
30只普通绵耳狨猴血液学和血清生化指标的测定及分析
Detection and analysis of hematological and serum biochemical indices of thirty common marmosets
摘要
Abstract
Objective To examine hematological and biochemical parameters in 30 common marmosets,count the mean and standard deviations of each index, and analyze significant differences between female and male groups. Additionally,data from marmosets and macaque breeding were compared. Methods Blood was collected through the posterior limb vein while animals were awake. Hematology and serum biochemical indices were then measured with an automatic blood cell analyzer and blood biochemical analyzer, followed by statistical testing. Results No significant differences were measured in hematological indices between male and female groups. There was a significant difference between the female and male group in serum biochemical indices including high-density lipoprotein-cholesterol(HDL-C) and low-density lipoprotein-cholesterol(LDL-C)(P < 0.05). Compared with the foreign marmoset group, HGB, MCHC,NEUT,ALT, AST, and GLOB were visibly increased in the group of marmosets fed by our institution, but in accordance with the data range in rhesus monkeys. Conclusions Hematological and serum biochemical indices of common marmosets have been detected in this study and compared with related data in macaques and marmosets. Our findings provide basic data not only for pharmacological and toxicological studies,but also diagnosis and treatment of diseases.关键词
普通绵耳狨猴/血液学指标/血清生化指标Key words
common marmosets/hematological indices/serum biochemical indices分类
医药卫生引用本文复制引用
滕永康,丛日旭,刘云波..30只普通绵耳狨猴血液学和血清生化指标的测定及分析[J].中国比较医学杂志,2018,28(5):70-74,5.基金项目
国家重点研发计划(编号:2017YFA0105201) （编号:2017YFA0105201）
北京市科技计划(编号:Z161100000216154). （编号:Z161100000216154）
