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固体纳米孔分析技术的研究进展

李志 刘丽萍 房真 郗冬梅

分析化学2018,Vol.46Issue(6):836-842,7.
分析化学2018,Vol.46Issue(6):836-842,7.DOI:10.11895/j.issn.0253-3820.181217

固体纳米孔分析技术的研究进展

Progress in Solid-state Nanopore-based Analysis Technology

李志 1刘丽萍 2房真 1郗冬梅1

作者信息

  • 1. 临沂大学化学化工学院, 山东省肿瘤标志物检测技术重点实验室, 临沂 276005
  • 2. 山东农业大学, 化学与材料科学学院, 泰安 271018
  • 折叠

摘要

Abstract

Nanopore technique is a low-cost tool for single-molecule level analysis without the need of label or amplification. The solid nanopores have been widely used in many fields such as chemistry and life sciences due to their advantages such as high stability, good tolerability, controllable size, and easy for modification. The solid nanopores commonly used in recent years are fabricated using two types of materials: membrane and tube. The membrane materials include silicon nitride, two-dimensional materials, aluminium oxide, and polymer membranes. The tube materials mainly include glass capillary and carbon nanotube. This review summarizes and prospects the research progress of different solid nanopores.

关键词

固体纳米孔/单分子分析/DNA测序/评述

Key words

Solid nanopore/Single-molecule analysis/DNA sequencing/Review

引用本文复制引用

李志,刘丽萍,房真,郗冬梅..固体纳米孔分析技术的研究进展[J].分析化学,2018,46(6):836-842,7.

基金项目

本文系国家自然科学基金项目(Nos. 21405073, 21535002)资助 This work was supported by the National Natural Science Foundation of China (Nos. 21405073, 21535002). (Nos. 21405073, 21535002)

分析化学

OA北大核心CSCDCSTPCD

0253-3820

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