摘要
Abstract
Objective To investigate the clinical features and prognosis of patients with acute posterior circulation infarction and severe stenosis or occlusion of both vertebral arteries/basilar artery.Methods A retrospective analysis was performed for the clinical data of patients with acute posterior circulation infarction and severe stenosis or occlusion of both vertebral arteries/basilar artery.The vascular risk factors,initial symptoms,treatment,and disease evolution were analyzed.The patients were followed up for 90 days,and a modified Rankin Scale score of ＞ 2 was defined as poor prognosis.Results A total of 28 patients were enrolled,and the most common initial symptom was isolated dizziness or vertigo,which occurred in 57.1％ of all patients.Of all patients,53.6％ experienced aggravation,and 9 (32.1％) had ≥2 times of aggravation;15 (53.6％) had poor prognosis.Compared with the good prognosis group,the poor prognosis group had a significantly higher proportion of patients with grade 3 hypertension,aggravation,or ≥2 times of aggravation (P ＜ 0.05).Compared with the aggravation ＜ 2 times group,the aggravation ≥2 times group had a significantly higher proportion of patients with grade 3 hypertension,hyperlipidemia,an initial symptom of isolated vertigo/dizziness,poor prognosis,or death (P ＜ 0.05).The patients with no image of the basilar artery had a significantly higher mortality rate than those with the image of the basilar artery (75％ vs 4.2％,P ＜ 0.05).Conclusions Patients with acute posterior circulation infarction and severe stenosis or occlusion of both vertebral arteries/basilar artery often have an initial symptom of isolated dizziness or vertigo.Patients with an initial symptom of isolated dizziness or vertigo and grade 3 hypertension tend to experience disease aggravation.Patients with frequent aggravation have a high proportion of patients with poor prognosis and a high mortality rate.Patients with no image of the basilar artery have a high mortality rate.关键词
后循环梗死/双侧椎动脉狭窄或闭塞/基底动脉狭窄或闭塞/孤立性头晕或眩晕Key words
posterior circulation infarction/stenosis or occlusion of both vertebral arteries/stenosis or occlusion of the basilar artery/isolated dizziness or vertigo
