国际神经病学神经外科学杂志2018，Vol.45Issue(2)：138-142,5.DOI:10.16636/j.cnki.jinn.2018.02.008
颅内多发动脉瘤个体化治疗研究及预后分析
Individualized treatment and prognostic analysis of multiple intracranial aneurysms
摘要
Abstract
Objective To investigate the individualized treatment of multiple intracranial aneurysms (MIAs) and the prognostic factors for MIAs.Methods A retrospective analysis was performed on the complete clinical data of 106 patients with MIAs.Univariate analysis and multivariate logistic regression analysis were used to analyze the effects of different preoperative factors and treatment regimens on treatment outcomes of the patients with MIAs.Results Of the 106 patients,85 had a higher Glasgow Outcome Scale (GOS) score (4-5),indicating good prognosis,and 21 had a lower GOS score (1-3),indicating poor prognosis.GOS scores for different treatment groups:45 of 58 patients undergoing surgery had a good prognosis (GOS 4-5);37 of 44 patients receiving interventional embolization had a good prognosis (GOS 4-5);3 of 4 patients undergoing surgery combined with interventional embolization had a good prognosis (GOS 4-5).Univariate analysis showed that age,location,and preoperative Fisher grade and Hunt-Hess grade of MIAswere associated with prognosis (P ＜ 0.05).Multivariate logistic regression analysis showed that age,location,and Fisher grade of MIAs were associated with prognosis (P ＜ 0.05).Conclusions Age,location,and preoperative Fisher grade and Hunt-Hess grade are key factors affecting the treatment outcomes of patients with MIAs.According to the actual condition of patients,choosing individualized treatment regimen (such as craniotomy,interventional embolization,and craniotomy combined with interventional embolization) is the key to improving the prognosis of patients with MIAs.关键词
颅内多发动脉瘤/个体化治疗/预后Key words
Multiple intracranial aneurysms/Individualized treatment/Prognosis引用本文复制引用
刘维生,郑月华,李爱军,卜振富,曹培成,王道奎..颅内多发动脉瘤个体化治疗研究及预后分析[J].国际神经病学神经外科学杂志,2018,45(2):138-142,5.基金项目
山东省医药卫生科技发展计划(2017WS248),潍坊市科技发展计划(2014WS081). （2017WS248）
