厄贝沙坦氢氯噻嗪对高血压患者血管内皮功能、血流动力学及炎症反应的影响OACSTPCD
Effect of irbesartan hydrochlorothiazide on endothelial function, hemodynamics and inflammatory response in hypertensive patients
目的:观察厄贝沙坦氢氯噻嗪对高血压患者血管内皮功能、血流动力学及炎症反应的影响.方法:选择就诊于我院的原发性高血压患者100例为研究对象,根据随机数字表法分为对照组和观察组.对照组50例行常规治疗,观察组50例在此常规治疗基础上口服厄贝沙坦氢氯噻嗪治疗.比较两组血管内皮功能、血流动力学及炎症因子水平的变化.结果:治疗前,两组vWF、EDD、NMD水平,血液流变学水平以及炎性因子水平比较差异无统计学意义(P＞0.05).与治疗前相比,治疗后观察组v…查看全部>>
Objective:To observe the effect of irbesartan hydrochloride on endothelial function,hemodynamics and inflammatory response in patients with essential hypertension.Method:A total of 100 patients with essential hypertension admitted from May 2015 to August 2017 in our hospital were divided into observation group (n =50) and control group (n =50) according to random number table.Thecontrol group was treated with routine treatment,and the observation group was t…查看全部>>
戈陈艳;杜林哲;张雪萌;焦娇;石婷
南京医科大学附属南京医院(南京市第一医院)药学部,江苏南京210006南京医科大学附属南京医院(南京市第一医院)药学部,江苏南京210006南京医科大学附属南京医院(南京市第一医院)药学部,江苏南京210006南京医科大学附属南京医院(南京市第一医院)药学部,江苏南京210006南京医科大学附属南京医院(南京市第一医院)药学部,江苏南京210006
医药卫生
厄贝沙坦氢氯噻嗪高血压血管内皮功能血流动力学炎症反应
Irbesartan hydrochlorothiazideHypertensionEndothelial functionHemodynamicsInflammatory reaction
《海南医学院学报》 2018 (8)
841-844,848,5
This study was supported by Natural Science Foundation of Jiangsu Province(Grant No.BK2015129).江苏省自然科学基金资助(BK2015129)
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