解放军医药杂志2018，Vol.30Issue(5)：83-85,3.DOI:10.3969/j.issn.2095-140X.2018.05.021
A型肉毒毒素对幼龄脑瘫患儿腓肠肌痉挛的影响
Effect of Botulinum Toxin A on Sural Spasm in Young Children with Cerebral Palsy
摘要
Abstract
Objective To investigate effect of Botulinum Toxin A on sural spasm in young children with cerebral palsy. Methods A total of 96 young children with cerebral palsy admitted during June 2014 and February 2016 were di-vided into observation group and control group. Control group received 4 course of routine rehabilitation training, while control group was added with Botulinum Toxin A injections on the basis of treatment for control group. Degrees of sural spasm, muscle tonus and gross motor function before and after treatment were compared in two groups. Results Before treatment, there were no significant differences in modified Ashworth scales (MAS) quantitative score, gastrocnemius surface electromyography (sEMG) values and gross motor function measure (GMFM) score between two groups (P >0. 05). After treatment, MAS quantitative scores and gastrocnemius sEMG values were significantly lower than those be-fore treatment in two groups, but the scores and values in observation group were significantly lower than those in control group (P < 0. 05); GMFM scores were significantly higher than those before treatment in two groups, and the score in ob-servation group was significantly higher than that in control group(P < 0. 05). Conclusion Botulinum Toxin A may ob-viously improve the degree on sural spasm in young children with cerebral palsy.关键词
脑性瘫痪/肉毒毒素类/儿童/肌痉挛Key words
Cerebral palsy/Botulinum toxin/Child/Muscle spasm分类
医药卫生引用本文复制引用
蔡志军,李巧秀,许令,王军..A型肉毒毒素对幼龄脑瘫患儿腓肠肌痉挛的影响[J].解放军医药杂志,2018,30(5):83-85,3.基金项目
郑州市技术研究与开发经费支持项目(153PKJGG164) （153PKJGG164）
