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首页|期刊导航|华西口腔医学杂志|唾液蛋白质糖基化及其与全身和口腔疾病关系的研究进展

唾液蛋白质糖基化及其与全身和口腔疾病关系的研究进展

马瑞 彭显 徐屹 段丁瑜

华西口腔医学杂志2018,Vol.36Issue(3):336-341,6.
华西口腔医学杂志2018,Vol.36Issue(3):336-341,6.DOI:10.7518/hxkq.2018.03.020

唾液蛋白质糖基化及其与全身和口腔疾病关系的研究进展

Advances in salivary protein glycosylation and its relationship with systemic and oral diseases

马瑞 1彭显 1徐屹 1段丁瑜1

作者信息

  • 1. 口腔疾病研究国家重点实验室 国家口腔疾病临床医学研究中心 四川大学华西口腔医院牙周病科,成都 610041
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摘要

Abstract

Protein glycosylation is one of the most important protein post-translational modifications that can affect life activities by endowing the protein with various structural and functional features. Saliva is an easy-to-obtain, noninvasive body fluid that contains components originating from serum, gingival crevicular fluid, and oropharyngeal mucosae. In recent years, understanding of saliva has been constantly updated with the developments in related research. Studies have shown that salivary proteins can be used as diagnostic markers for certain diseases, and changes of protein glycosylation in saliva are generally considered to be related to many diseases. In this review, salivary protein glycosylation and its relationship with systemic and oral diseases were discussed.

关键词

蛋白质翻译后修饰/糖基化/唾液/全身系统疾病/口腔疾病

Key words

protein post-translational modification/glycosylation/saliva/systemic diseases/oral diseases

分类

生物科学

引用本文复制引用

马瑞,彭显,徐屹,段丁瑜..唾液蛋白质糖基化及其与全身和口腔疾病关系的研究进展[J].华西口腔医学杂志,2018,36(3):336-341,6.

基金项目

国家自然科学基金(81700984)Supported by: The National Natural Science Foundation of China (81700984). (81700984)

华西口腔医学杂志

OA北大核心CSCDCSTPCDMEDLINE

1000-1182

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