检验医学与临床2018，Vol.15Issue(11)：1606-1608,1612,4.DOI:10.3969/j.issn.1672-9455.2018.11.021
哮喘-慢性阻塞性肺疾病重叠综合征急性加重期血清PCT、总IgE检测的意义
Significance of detection of serum PCT and total IgE in patients with acute exacerbation of asthma-chronic obstructive pulmonary disease overlap syndrome
肖翔 1陈艳清 1贾健 1李瑞金 2方佳 3钟阳青1
作者信息
- 1. 广东省东莞市塘厦医院检验科 523721
- 2. 广东省东莞市塘厦医院急诊科 523721
- 3. 广东省东莞市塘厦医院内科 523721
- 折叠
摘要
Abstract
Objective To investigate the expression and clinical significance of serum procalcitonin (PCT ) and total IgE (T-IgE) in patients with acute exacerbation of asthma-chronic obstructive pulmonary disease o-verlap syndrome (ACOS) .Methods A total of 44 patients with acute exacerbation of ACOS ,51 patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD ) ,47 patients with acute attack of bronchial asthma were enrolled in the study ,and all the cases were examined for serum PCT and T-IgE .Re-sults The levels of PCT in the two groups of ACOS and AECOPD were significantly higher than that in the asthma group ,the differences were statistically significant (P<0 .05) ,but there was no statistical significance in PCT levels between ACOS group and AECOPD group (P>0 .05);the levels of T-IgE in ACOS group and asthma group were significantly higher than that in AECOPD group ,the differences were statistically signifi-cant (P<0 .05) ,but there was no statistical significance in T-IgE levels between ACOS group and asthma group (P>0 .05) .With PCT ≥0 .25 ng/mL as critical value ,the positive rates of PCT and T-IgE in 3 groups were 75 .00％ ,78 .41％ ,19 .15％ and 65 .91％ ,9 .80％ ,78 .72％ respectively ,and the positive rates of PCT and T-IgE in ACOS group were both 40 .91％ .Conclusion The value of serum PCT and T-IgE in identifying the diseases in three groups are low ,but the increase of PCT and T-IgE at the same time may be considered as the auxiliary diagnostic basis of ACOS .There may be different phenotypes in ACOS acute attack .关键词
哮喘-慢性阻塞性肺重叠综合征/降钙素原/总IgEKey words
asthma-chronic obstructive pulmonary disease overlap syndrome/procalcitonin/total IgE分类
临床医学引用本文复制引用
肖翔,陈艳清,贾健,李瑞金,方佳,钟阳青..哮喘-慢性阻塞性肺疾病重叠综合征急性加重期血清PCT、总IgE检测的意义[J].检验医学与临床,2018,15(11):1606-1608,1612,4.
