中南医学科学杂志2018，Vol.46Issue(3)：232-235,246,5.DOI:10.15972/j.cnki.43-1509/r.2018.03.002
Wilms肿瘤基因在生长发育及非肿瘤性疾病中作用研究
The research of Wilms' tumor gene in growth and non-neoplastic diseases
摘要
Abstract
The Wilms' tumor 1gene ( WT1) encodes a zinc finger transcription factor and is associated with wilms' tumor. Recent studies have shown that WT1 is indispensable for normal development of many organs and tissues. Besides acting as a tumor suppressor or proto-oncogene, WT1 is also closely related to many non-neoplastic diseases such as obesi-ty, diabetes and hypertension. This article mainly focuses on participation of WT1 gene in physiological development as well as in multiple diseases.关键词
Wilms肿瘤基因/发育/疾病/生物学功能Key words
WT1/development/diseases/biological function分类
医药卫生引用本文复制引用
陈俊玲,杨芝春..Wilms肿瘤基因在生长发育及非肿瘤性疾病中作用研究[J].中南医学科学杂志,2018,46(3):232-235,246,5.基金项目
国家自然科学基金面上项目(No.81673491) （No.81673491）
湖南省自然科学基金( No.2015JJ3140) . （ No.2015JJ3140）
