山东医药2018，Vol.58Issue(9)：5-8,4.DOI:10.3969/j.issn.1002-266X.2018.09.002
Gd-EOB-DTPA增强MRI在大范围肝切除术后肝衰竭风险评估中的作用
Role of Gd-EOB-DTPA-enhanced MRI in assessing the risk of liver failure after major liver resection
摘要
Abstract
Objective To investigate the role of Gd-EOB-DTPA-enhanced MRI in assessing the risk of liver failure after major liver resection.Methods Thirty-six patients with three or more segments of the liver partial resection were enrolled.All patients underwent Gd-EOB-DTPA-enhanced MRI,liver-enhanced CT,ICG clearance test,Child-Pugh score,and liver function serum test for preoperative checkup.The relationships of preoperative liver function,remnent hepatocellular uptake index (rHUI),standard remnant hepatocellular uptake index (SrHUI) and intraoperative relevant indicators with postoperative liver failure risk were analyzed.We used the receiver operating characteristic curve (ROC) to evaluate the diagnostic value of rHUI and SrHUI in predicting the risk of liver failure.Results Eight patients (22.22％) experienced the risk of hepatic failure.There were significant differences in the rHUI,SrHUI,and albumin of patients with the risk of liver failure and without the risk (all P ＜ 0.05).The ROC area under the curve (AUC) of rHUI and SrHUI was 0.835 and 0.864,respectively (sensitivity:71.4％ and 85.7％,specificity:87.5％ and 75.0％,cut-off value:0.614 and 0.344,95％ confidence interval:0.654-0.947 and 0.730-0.998).Conclusion Gd-EOB-DTPA-enhanced MRI can accurately assess the residual liver function,and has important significance in assessing the risk of liver failure after major liver resection.关键词
肝肿瘤/肝衰竭/钆塞酸二钠增强MRI/肝切除Key words
liver neoplasms/hepatic failure/Gd-EOB-DTPA-enhanced MRI/hepatectomy分类
医药卫生引用本文复制引用
余前军,程龙,朱永强,杜飞舟,黄民,汪涛..Gd-EOB-DTPA增强MRI在大范围肝切除术后肝衰竭风险评估中的作用[J].山东医药,2018,58(9):5-8,4.基金项目
国家自然科学基金资助项目(81300280) （81300280）
四川省青年科技基金项目(2016JQ0023). （2016JQ0023）
