世界中医药2018，Vol.13Issue(5)：1123-1126,4.DOI:10.3969/j.issn.1673-7202.2018.05.018
益气活血中药对肝癌放疗后肝脏微循环及肝纤维化指标的影响
Effects of Yiqi Huoxue Herbs on Liver Microcirculation and Hepatic Fibrosis Indexes for Primary Liver Cancer after Radiotherapy
摘要
Abstract
Objective:To explore the effect of Yiqi Huoxue herbs on liver microcirculation and hepatic fibrosis indexes for primary liver cancer ( PLC) after radiotherapy .Methods:A total of 62 cases of PLC patients in our hospital from January 2016 to January 2017 were selected and randomly divided into control group and treatment group , with 31 cases in each group .Control group was treated with three dimensional conformal radiotherapy , and treatment group was treated with Yiqi Huoxue herbs on the basis of con-trol group.Recent clinical curative effect of 2 groups was statisticsed , and TCM symptoms integral change of 2 groups before and after treatment was evaluated .The change of nailfold microcirculation and hepatic fibrosis indexes of 2 groups before and after treatment was detected and compared .Results:The total remission rate of 2 groups had no significant difference (P>0.05).The total stability rate of treatment group was 96.77％, which was significantly higher than 77.42％ of control group ( P<0.05 );Compared with before treatment , the TCM symptoms integral of abdominal distention , poor appetite, nausea, vomiting, fatigue, pain and jaundice of treatment group after treatment significantly declined , and which in treatment group were significantly lower than that in control group ( P<0.05 or P<0.01);Compared with before treatment , the hepatic fibrosis indexes of HA , PC-Ⅲ, C-Ⅳand LN of 2 groups increased significantly , and the integral of week state of loops , tube shape of loops , flow pattern and total integral decreased significantly .The above indicators in treatment group were lower than that in control group ( P<0.05 or P<0.01).Conclusion:Yiqi Huoxue herbs combined with radiotherapy can obviously improve the liver microcirculation of the patients with PLC, reduce the degree of hepatic fibrosis , increase the stability rate of lesions , and reduce patients′pain.关键词
原发性肝癌/益气活血中药/放疗/肝纤维化/微循环Key words
Primary liver cancer/Yiqi huoxue herbs/Radiotherapy/Hepatic fibrosis/Microcirculation分类
医药卫生引用本文复制引用
石相如,章凯敏,徐晓娅..益气活血中药对肝癌放疗后肝脏微循环及肝纤维化指标的影响[J].世界中医药,2018,13(5):1123-1126,4.基金项目
咸宁市科学技术研究与开发项目(20150402) （20150402）
