世界中医药2018，Vol.13Issue(5)：1198-1201,4.DOI:10.3969/j.issn.1673-7202.2018.05.037
麝香保心丸联合阿托伐他汀治疗急性心肌梗死的疗效观察
Effect of Shexiang Baoxin Pill Combined with Atorvastatin on Acute Myocardial Infarction and Its Effect on Vascular Endothelial Function and Cardiac Function
摘要
Abstract
Objective:To investigate the effect of Shexiang Baoxin Pill combined with atorvastatin on acute myocardial infarction ( AMI) and its effect on vascular endothelial function and cardiac function .Methods:A total of 81 patients admitted to our hospi-tal from October 2013 to September 2016 were included in the study and randomized to receive routine treatment .Forty patients in the control group were treated with atorvastatin and 41 patients in the control group was given Shexiang Baoxin Pill based on the control group, with 14 days for a course of treatment .Brain natriuretic peptide (BNP), left ventricular ejection fraction (LVEF), left ventricular end-diastolic dimension (LVEDD), left ventricular end-diastolic diameter (LVESD), nitric oxide (NO), endothe-lin (ET), and other vascular endothelial function and high sensitivity C-reactive protein (Hs-CRP) before and after treatment were compared.The clinical efficacy and complications were compared .Results:After treatment, the levels of BNP, Hs-CRP, LVEDD, LVESD and ET were decreased , and LVEF and NO were increased .The improvement was significant in the observation group (P<0.05).The total effective rate of the control group was 70.00％ (28/40) (P<0.05).The incidence of complica-tions was lower in the observation group (P<0.05), and the total effective rate was higher (P<0.05).Conclusion:Shexiang Baoxin Pill combined with atorvastatin has a significant effect in the treatment of AMI , which can better protect heart function and endothelial function .关键词
麝香保心丸/阿托伐他汀/急性心肌梗死/血管内皮功能/心功能Key words
Shexiang Baoxin pill/Atorvastatin/Acute myocardial infarction/Vascular endothelial function/Cardiac function分类
医药卫生引用本文复制引用
熊巍,叶华,佘姝娅,何林..麝香保心丸联合阿托伐他汀治疗急性心肌梗死的疗效观察[J].世界中医药,2018,13(5):1198-1201,4.基金项目
四川省中医药管理局科技专项立项课题(2012-G-033) （2012-G-033）
