疑难病杂志2018，Vol.17Issue(5)：534-537,4.DOI:10.3969/j.issn.1671-6450.2018.05.027
细胞信号通路影响肾间质纤维化的研究新进展
Updates of cellular signaling pathway on renal interstitial fibrosis
摘要
Abstract
Renal interstitial fibrosis (RIF) is an irreversible process of chronic kidney disease and renal failure characterized by numerous fibroblast proliferation,uncontrolled deposits of extracellular matrix,and progressive loss of renal function.In the pathological stage,a variety of signaling pathways are involved and interact with each other,which play an important role in the development of renal fibrosis.Therefore,it is significant to comprehend the pathogenesis of RIF and find specific targets for the treatment.This article reviews the current research progress in RIF mediated by signaling transduction pathways to provide a new direction for the treatment of RIF.关键词
肾间质纤维化/肌成纤维细胞/信号通路Key words
Renal interstitial fibrosis/Muscle fibroblast/Signaling pathway引用本文复制引用
杨康..细胞信号通路影响肾间质纤维化的研究新进展[J].疑难病杂志,2018,17(5):534-537,4.基金项目
国家自然科学基金资助项目(81470923) （81470923）
