中风与神经疾病杂志2018，Vol.35Issue(5)：420-424,5.
高分辨MRI大脑中动脉管壁改变与脑白质高信号相关因素分析
Middle cerebral arterial wall changes on high-resolution MRI and white matter hyperintensity:Correlation with relevant factors
摘要
Abstract
Objective To investigate the correlation between the changes of middle cerebral artery ( MCA) wall and the severity of brain cerebral white matter hyperintensity ( WMH) and the risk factors associated with cerebral vascular dis-ease in patients who perform MRI image screening with acute cerebral infarction .Methods We collected 86 cases of pa-tients with acute ischemic stroke diagnosed by DWI and recorded patients medical history ,changes of MCA wall and the sig-nal level of cerebral white matter hyperintensity severity by means of MRI T 2 W,FLAIR and MCA in HRMRI .The risk fac-tors were analyzed according to MCA wall changes and WMH and the independent predictors of the two were analyzed by Logistic regression.Results Three cases of poor image quality were excluded ,and 83 cases were included in the study . There were 37 cases of significant WMH (2,3 points) in the T2FLAIR image,and 46 cases without significant WMH (0, 1).There was a significant correlation between WMH and age ,mRs score,hypertension,diabetes mellitus and MCA wall changes (P<0.05).Hypertension and MCA wall changes were significantly associated with WMH by Logistic regression . In this study,there were 38 cases of severe MCA wall changes (2,3 points) and 45 cases with no changes (0,1),and the difference with age , hypertension and diabetes was statistically significant .The Logistic regression showed that age was closely related to the severity of MCA wall changes in the brain .Conclusion WMH has a higher incidence in patients with cerebrovascular disease and is closely related to age ,mRs score,hypertension,diabetes and MCA wall changes .Early detection of MCA wall changes and take appropriate intervention measures for prevention of WMH has important clinical sig -nificance .关键词
脑白质高信号/高分辨磁共振成像/三维等体素快速自旋回波采集序列/动脉粥样硬化Key words
White matter hyperintensity/High resolution magnetic resonance imaging/Three-dimensional volu-metric isotropic Turbo spin echo acquisition/Atherosclerosis分类
医药卫生引用本文复制引用
刘天怡,杨诗琪,赵庆龙,李国忠,钟镝,陈洪苹..高分辨MRI大脑中动脉管壁改变与脑白质高信号相关因素分析[J].中风与神经疾病杂志,2018,35(5):420-424,5.基金项目
黑龙江省科技攻关计划,黑龙江省社会科学基金资助项目(GA14C101-04) （GA14C101-04）
