中国骨伤2018，Vol.31Issue(5)：488-492,5.DOI:10.3969/j.issn.1003-0034.2018.05.018
诱导膜技术治疗大段骨缺损研究进展
Research progress on induced membrane technique for the treatment of segmental bone defect
摘要
Abstract
Treatment of large bone defects caused by trauma,osteomyelitis,and tumors has been a major challenge in clinical.In the past,there have been many ways to repair and reconstruct the large bone defects.However,there is a long period of treatment,high technical requirement and complications such as ununion.After Masquelet reported the induced membrane technology in 2000,the technique was widely used in treatment of trauma,osteomyelitis,and large bone defects caused by tumors.it has been obtained good results.It has the advantages of short course,high healing rate,easy operation and easy to master.The induced membrane has unique structural characteristics and biological characteristics.There are many kinds of osteogenic factors that are included in the membrane,such as vascular endothelial growth factor,and morphogenetic protein-2,transforming growth factor-β1,etc.These osteogenic factors contribute to accelerate bone healing.With the development of induced membrane technology.The technology of Reamer Irrigator Aspirator technology,engineering tissue technology and internal fixation is used in clinic.It can provide bone source,promote bone defect reconstruction,improve long-term limb function and reduce complications.This paper retrospectively summarizes the experimental research and clinical progress of Masquelet technique in the treatment of large bone defects.关键词
诱导膜/骨缺损/综述文献Key words
Induced membrane/Bone defect/Review literature引用本文复制引用
金志超,蔡群斌,曾志奎,李定,李悦,黄培镇,郑晓辉..诱导膜技术治疗大段骨缺损研究进展[J].中国骨伤,2018,31(5):488-492,5.基金项目
国家自然科学基金资助项目(编号:8160150894) （编号:8160150894）
广东省中医药管理局项目(编号:20161135,20161129).National Natural Science Foundation of China (No.8160150894) （编号:20161135,20161129）
