中国现代医学杂志2018，Vol.28Issue(15)：71-74,4.DOI:10.3969/j.issn.1005-8982.2018.15.015
恙虫病并发多器官功能障碍综合征及死亡预测因素研究
Predictive factors of multiple organ disfunction syndrome and death in patients with scrub typhus
摘要
Abstract
Objective To investigate the predictive factors of multiple organ disfunction syndrome (MODS) or death in patients with scrub typhus. Methods A total of 268 cases of scrub typhus were involved in this study, among which were 17 cases with MODS. Clinical information were recorded and analyzed. Result Patients in MODS group experienced increased incidence of leukocytosis, thrombocytopenia, elevated levels of serum creatinine (SCr), and procalcitonin > 0.5 μg/L compared with non-MODS group (P < 0.05). Multivariate logistic regression analysis showed thrombocytopenia and elevated levels of SCr were independent predictive factors of MODS (O(R) = 19.014, 95％ CI: 4.239, 85.280, Ol(R) = 113.286, 95％ CI: 29.3914, 36.649, respectively). Occurrence of organ failure (from highest to lowest) was as follows: blood coagulation, lung, peripheral blood circulation, heart, brain, liver, kidney, gastrointestinal tract and metabolism. Incidence of acute respiratory distress syndrome in MODS group were dramatically increased compared with non-MODS group (P < 0.05). Conclusion Thrombocytopenia and elevated levels of SCr are associated with the occurrence of MODS, and ARDS indicates poor prognosis in patients with scrub typhus.关键词
恙虫病/多器官功能障碍综合征/死亡/预测因素Key words
scrub typhus/multiple organ disfunction syndrome/death/predictive factors分类
医药卫生引用本文复制引用
韩焕钦,杜谕君,张丽敏,邓威,张武英,陈长虹..恙虫病并发多器官功能障碍综合征及死亡预测因素研究[J].中国现代医学杂志,2018,28(15):71-74,4.基金项目
广东省医学科学技术研究基金(No:A2017455) （No:A2017455）
广东省湛江市科技攻关计划项目(No:2017B01114) （No:2017B01114）
