中国药房2018，Vol.29Issue(10)：1332-1334,3.DOI:10.6039/j.issn.1001-0408.2018.10.09
正交试验优化参芪妇康颗粒的提取工艺
Optimization of Extraction Technology of Shenqi Fukang Granules by Orthogonal Test
摘要
Abstract
OBJECTIVE:To optimize extraction technology of Shenqi fukang granules. METHODS:Single factor method was used to investigate water multiple at first time using water absorption as index,soaking time using yield of dry extract as index. Based on single factor test,by weighted comprehensive scoring method,using the yield of dry extract and the content of 75％ ethanol extraction as indexes,extraction time,water multiple and extraction times as factors,L9(34) orthogonal test was used to optimize water extraction technology of Shenqi fukang granules. Validation test was conducted. RESULTS:The optimal water extraction technology included 8-fold water (L/kg), extracting for 3 times, 1 h each time. CONCLUSIONS:The optimized extraction technology is stable and controllable in quality,and can provide reference for industrial production of Shenqi fukang granules.关键词
参芪妇康颗粒/提取工艺/正交试验/干膏得率/乙醇浸出物含量Key words
Shenqi fukang granules/Extraction technology/Orthogonal test/Yield of drug extract/Content of ethanol extract分类
医药卫生引用本文复制引用
孙臻,张影,汪杰,陈明聪,黄祖光,高华宏..正交试验优化参芪妇康颗粒的提取工艺[J].中国药房,2018,29(10):1332-1334,3.基金项目
三亚市医疗卫生科技创新项目(No.2016YW03) （No.2016YW03）
