中国药房2018，Vol.29Issue(11)：1532-1536,5.DOI:10.6039/j.issn.1001-0408.2018.11.22
炮制方法及提取溶剂对何首乌中主要成分含量的影响
Effects of Processing Methods and Extraction Solvents on the Contents of Major Components in Polygonum multiflorum
摘要
Abstract
OBJECTIVE:To study the effects of different processing methods and extraction solvents on the contents of major components in Polygonum multiflorum. METHODS:Decoction of black soybean and water were used to steam the raw P.multiflorum. Water,50％ ethanol,70％ ethanol and 90％ ethanol were used to extract the raw,black soybean steamed,water steamed and commercial processed P. multiflorum respectively. HPLC method was used to detect the contents of gallic acid,2,3,5, 4′-tetrahydroxystilbene-2-O-β-D-glucoside (THSG),emodin and physcion. RESULTS:The contents of 4 major components in 4 kinds of extracts from 3 kinds of processed P. multiflorum were higher than raw sample;the content of gallic acid extracted with water was the highest;the content of THSG extracted with 90％ ethanol was the lowest;the contents of emodin and physcione extracted with 50％ and 70％ ethanol were the higher. CONCLUSIONS:Different processing methods and different extraction solvents had effect on the contents of the main compounds of P. multiflorum. The contents of each components in the processing products didn't show certain regularity.关键词
何首乌/炮制方法/提取溶剂/没食子酸/二苯乙烯苷/大黄素/大黄素甲醚/含量Key words
Polygonum multiflorum/Processing method/Extraction solvent/Gallic acid/2/3/5/4′-tetrahydroxystilbene-2-O-β-D-glucoside/Emodin/Physcion/Content分类
医药卫生引用本文复制引用
朱敏,姚毅,居文政,刘志辉,方祝元..炮制方法及提取溶剂对何首乌中主要成分含量的影响[J].中国药房,2018,29(11):1532-1536,5.基金项目
江苏省中医药局科技项目(No.YB2015029) （No.YB2015029）
