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前列腺癌转移动物模型特性的比较学分析

饶玉良 孙祖越

中国药理学通报2018,Vol.34Issue(6):760-764,5.
中国药理学通报2018,Vol.34Issue(6):760-764,5.DOI:10.3969/j.issn.1001-1978.2018.06.006

前列腺癌转移动物模型特性的比较学分析

Advances in constructing metastatic animal models of prostate cancer

饶玉良 1孙祖越2

作者信息

  • 1. 上海市计划生育科学研究所药理毒理学研究室,中国生育调节药物毒理检测中心,上海 200032
  • 2. 复旦大学药学院,上海 200031
  • 折叠

摘要

Abstract

Prostate cancer is a common neoplasm of the genitou-rinary system for male, and tumor metastasis of prostate cancer is a common complication and a lethal factor. Researching on prostate cancer metastasis is very important for clinical research and treatment. Proper models of prostate cancer metastasis are important tools for the study of occurrence, progression, metas-tasis, and drug research for prostate cancer. This article intro-duces the common model of human prostate cancer metastasis, including the points of operation, evaluation, application of me-tastatic models and comparing the characteristics of various mod-els, to the benefit of researching and selecting models of prostate cancer.

关键词

前列腺癌/动物模型/肿瘤转移/转移模型/评价方法/人源组织异种移植PDX

Key words

prostate cancer/animal model/tumor metastasis/metastasis model/evaluation method/patient-derived tumor xen-ograft

分类

医药卫生

引用本文复制引用

饶玉良,孙祖越..前列腺癌转移动物模型特性的比较学分析[J].中国药理学通报,2018,34(6):760-764,5.

基金项目

上海市"科技创新行动计划"实验动物研究领域科技支撑项目( No 17140900801 ) ( No 17140900801 )

上海科技服务平台项目( No 17DZ2293600) ( No 17DZ2293600)

中国药理学通报

OA北大核心CSCDCSTPCD

1001-1978

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