广西医科大学学报2018，Vol.35Issue(6)：783-786,4.DOI:10.16190/j.cnki.45-1211/r.2018.06.010
心室颤动家兔QT变化与心肺复苏后恶性心律失常的关系
The relationship between alteration of the QT interval and malignant arrhythmia after cardiopulmonary resuscitation in a rabbit model of ventricular fibrillation
李海霄 1陈蒙华2
作者信息
- 1. 广西医科大学一附院心电诊断科,南宁530021
- 2. 广西医科大学第二附属医院心内科,南宁530007
- 折叠
摘要
Abstract
Objective:To observe the change of QT interval before and after successful cardiopulmonary resuscitation (CPR) in a rabbit model of ventricular fibrillation (VF).Methods:A rabbit model of VF was established and then began CPR.After successful resuscitation,the rabbits were divided into a malignant arrhythmia (MA) group and a non-MA group.The electrocardiogram was observed before VF and after successful restoration of spontaneous circulation (ROSC).Results:The survival rate was significantly lower in the MA group than that in non-MA group (P＜0.05).After successful ROSC,the QTc (corrected QT) and QTpc (corrected QTp) were notably shortened in the MA group (P＜0.05).At 15 min after ROSC,the QTc and QTpc were returned to the normal levels.However,there were no significant differences in QTc and QTpc in non-MA group before VF and after ROSC (P＞0.05).The QTpc in the MA group was significantly shorter than that in non-MA group after successful ROSC (P＜0.05).In the MA group,The corrected T peak-T end at the time of successful return of ROSC and 15 min after ROSC were significantly prolonged as compared with those before VF (P＜0.05).But no significant difference was found in non-MA group (P ＞0.05).Conclusion:The change of QT interval at early ROSC could predict occurrence of MA.Corrected T peak-T end was more sensitive than QTc and QTpc.关键词
心肺复苏/恶性心律失常/QT间期Key words
cardiopulmonary resuscitation/malignant arrhythmia/QT interval分类
医药卫生引用本文复制引用
李海霄,陈蒙华..心室颤动家兔QT变化与心肺复苏后恶性心律失常的关系[J].广西医科大学学报,2018,35(6):783-786,4.
