河北工业科技2018，Vol.35Issue(4)：294-298,5.DOI:10.7535/hbgykj.2018yx04012
舒筋通络颗粒中乳香挥发油提取及包合工艺研究
Study on extraction and inclusion process of volatile oil from frankincense in Shujintongluo granules
摘要
Abstract
In order to improve the stability of frankincense volatile oil in the preparation,the extraction and inclusion techno-logy of volatile oil from frankincense in Shujintongluo granules are studied.Four factors such as soaking time (A ),grain size (B ),water volume (C )and extraction time (D )are selected as the investigation factors.The extraction process of volatile oil from frankincense is optimized by L9 (34 ).Through the orthogonal experimental design,the two inclusion methods of saturated aqueous solution and colloidal grinding are studied.The result shows that the optimum combination is of influencing factors A1B1C1D3 ,the amount of water and the extraction time have very significant effect on the yield.In addition,the inclusion time,the proportion of volatile oil and beta cyclodextrin,and the inclusion temperature have extremely significant effect on the saturated aqueous solution;the grinding time,the volatile oil and the ratio of beta cyclodextrin have very significant influence on the colloidal grinding method.From the view point of production,the inclusion of the volatile oil of frankincense by the colloid grinding method is more advantageous than that by the saturated water solution method.关键词
中药药剂学/乳香挥发油/提取/包合/饱和水溶液法/胶体磨法/正交试验设计Key words
pharmacy of traditional Chinese medicine/volatile oil of frankincense/extraction/inclusion/saturated solution method/colloid grinding/orthogonal test design分类
医药卫生引用本文复制引用
屈云萍,李哲,王娇,李菲,杨斯斯,刘铁军..舒筋通络颗粒中乳香挥发油提取及包合工艺研究[J].河北工业科技,2018,35(4):294-298,5.基金项目
国家中医药管理局中医药科学技术研究专项课题(国中医药科 2013ZX07) （国中医药科 2013ZX07）
