临床神经外科杂志2018，Vol.15Issue(3)：174-178,5.DOI:10.3969/j.issn.1672-7770.2018.03.004
基于体素的磁共振形态学测量分析法检测局灶性皮质发育不良的临床应用
Voxel-based morphometric MRI analysis on detection of focal cortical dysplasia
摘要
Abstract
Objective To evaluate the value of voxel-based morphometric MRI analysis on detection of focal cortical dysplasia ( FCD) .Method 44 patients with histopathologically confirmed type I FCD from 2015 to 2016 were included in this study .The FCD detection rates of extension , junction and thickness images derived by morphometric analysis program ( MAP) were compared, and the detection rates of conventional visual analysis and MAP-assistant analysis were also compared .Results The FCD detection rates of junction and thickness images were higher than that of extension image .Neither conventional visual analysis nor MAP-assistant analysis detected type ⅠFCD lesions.However,MAP-assistant analysis improved detection of type ⅡFCD lesions,especially type ⅡA lesions(P=0.03,P=0.05).Conclusion MAP was useful in FCD lesion screening and confirming questionable abnormalities for epilepsy patients , but it had less effects on patients with reoperation or patients with strictly MRI negative FCD lesions .关键词
基于体素的形态学分析/磁共振/局灶性皮质发育不良/癫痫Key words
voxel-based morphometry/magnetic resonance imaging/focal cortical dysplasia/epilepsy分类
医药卫生引用本文复制引用
胡文瀚,王秀,张弨,桑林,郑重,张凯,邵晓秋,马延山,张建国..基于体素的磁共振形态学测量分析法检测局灶性皮质发育不良的临床应用[J].临床神经外科杂志,2018,15(3):174-178,5.基金项目
首都卫生发展科研专项(2016-1-1071) （2016-1-1071）
北京市自然科学基金(Z161100000216130,Z131107002213065) （Z161100000216130,Z131107002213065）
