临床神经外科杂志2018，Vol.15Issue(3)：184-186,3.DOI:10.3969/j.issn.1672-7770.2018.03.006
Ommaya囊置入术联合放化疗治疗囊性野生型肺腺癌脑转移瘤临床观察
Clinical observation on treatment of cystic lung adenocarcinoma with brain metastases through Ommaya sac implantation combined with radiation and chemotherapy
孟祥继 1徐军 1周士振 1王勇 1朱玉方 1陶荣杰1
作者信息
摘要
Abstract
Objective To observe the clinical efficacy of Ommaya sac implantation combined with radiation and chemotherapy for treatment of cystic brain metastases from lung adenocarcinoma . Methods Clinical efficacy and imaging results of 48 patients with cystic brain metastases from lung adenocarcinoma were analyzed retrospectively using the treatment of Ommaya sac implantation combined with radiation and chemotherapy .Results Various degrees of high intracranial pressure were observed in 48 patients before treatment ,which caused headache in 39 patients,vomit in 27 and blurred vision in 8. Focal nervous damages were observed including physical impairment in 27 patients,epileptic seizure in 12,defect of visual field in 10 and aphasia in 8.Improvement of clinical symptoms and activity of daily living were noted in 36 patients,imaging re-check indicated focus shrink <50%in 36 patients,enjoying an effective rate of 75%.Progressive disease was noted in 4 patients and deaths was noted in 3. Conclusion Treatment of cystic lung adenocarcinoma with brain metastases through Ommaya sac implantation combined with radiation therapy and chemotherapy is effective and safe .关键词
Ommaya囊置入术/放化疗/野生型肺腺癌/囊性转移瘤Key words
Ommaya sac/radiotherapy and chemotherapy/wild-type adenocarcinoma of lung/metastatic brain tumors分类
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孟祥继,徐军,周士振,王勇,朱玉方,陶荣杰..Ommaya囊置入术联合放化疗治疗囊性野生型肺腺癌脑转移瘤临床观察[J].临床神经外科杂志,2018,15(3):184-186,3.
