临床神经外科杂志2018，Vol.15Issue(3)：187-189,192,4.DOI:10.3969/j.issn.1672-7770.2018.03.007
脑室外引流术联合分次立体定向放射外科治疗巨大脑转移瘤
External ventricular drainage combined with fractionated stereotactic radiosurgery for a large brain metastasis
摘要
Abstract
Objectives The obstructive hydrocephalus caused by brain metastases may lead to severe intracranial hypertension ,which is a contraindication for salvage treatment such as radiotherapy . We presented a patient with a large brain metastasis in the right lateral ventricle trigone who achieved a good short-term therapeutic efficacy with external ventricular drainage ( EVD ) combined with fractionated stereotactic radiosurgery ( FSRS ) .Methods A 59-year-old woman was diagnosed lung adenocarcinoma for nine months before emergent admission .On admission ,the patient presented with cerebral hernia ,and the MRI showed a mass with a maximum diameter of 5.3 cm and a volume of 32.5 mL.The craniotomy was declined ,and we carried out EVD to relieve the obstructive hydrocephalus due to brain metastases ,followed by FSRS .Results Neurological symptoms were improved within one day after EVD and the quality of life was significantly improved after the completion of the treatment combining EVD with FSRS and WBRT .The patient had good outcome without progression in intracranial tumors for 5 months.Conclusion For obstructive hydrocephalus caused by brain metastases , EVD combined with FSRS could be considered as an emergent treatment to relieve symptoms quickly .关键词
脑转移瘤/梗阻性脑积水/脑室外引流术,分次立体定向放射外科Key words
brain metastasis/obstructive hydrocephalus/external ventricular drainage/fractionated stereotactic radiosurgery分类
医药卫生引用本文复制引用
甄俊杰,洪伟平,王辉,杨艳莹,山常国,赖名耀,蔡林波..脑室外引流术联合分次立体定向放射外科治疗巨大脑转移瘤[J].临床神经外科杂志,2018,15(3):187-189,192,4.基金项目
广东省自然科学基金(S2012010009620) （S2012010009620）
