临床神经外科杂志2018，Vol.15Issue(3)：218-222,5.DOI:10.3969/j.issn.1672-7770.2018.03.014
颅内血管外皮细胞瘤的治疗及预后影响因素分析
Analysis of treatment and prognostic factors of intracranial hemangiopericytoma
李彦东 1朱国华 2麦麦提力·米吉提 2王昀 2更·党木仁加甫2
作者信息
- 1. 830054 乌鲁木齐,新疆医科大学第一临床医学院
- 2. 第一附属医院神经外科
- 折叠
摘要
Abstract
Objective To investigate the treatment of intracranial hemangiopericytoma ( HPC) and its prognostic factors .Methods The clinical data of 31 patients with intracranial HPC were reviewed, and the clinical characteristics and related factors affecting the survival period were analyzed and summarized .Results 31 patients with intracranial HPC underwent surgical resection . 22 patients underwent complete resection and 9 total resection ( subtotal resection in 5, majority resection in 3,partial resection in 1).WHO grade Ⅱ had 12 cases and WHO grade Ⅲ in 19. Thirteen patients underwent extracranial radiation and 10 underwent γ-knife treatment .Follow-up time was 12 ~96 months, with a median of 65 months.The 5-year relapse-free survival rate was 53.8%in all patients,with a median recurrence-free survival (RFS) of 65 months.The median RFS was 76 months in the total resection group and 33 months in the non-total-cut group ( P<0 .01 ) . The median RFS was 76 months in patients receiving postoperative radiotherapy and 40 months in patients who underwent surgery alone ( P<0 .01 ) .The median RFS was 81 months in WHO gradeⅡ HPC patients and in WHO grade Ⅲpatients Median RFS was 40 months ( P <0.01 ). Conclusions Total resection of tumor and postoperative adjuvant radiotherapy can reduce the recurrence rate of HPC in situ and prolong the patient 's RFS.This is an effective treatment for intracranial HPC .关键词
血管外皮细胞瘤/神经外科手术/放射治疗/无复发生存期Key words
hemangiopericytoma/neurosurgery/radiotherapy/recurrence free survival分类
医药卫生引用本文复制引用
李彦东,朱国华,麦麦提力·米吉提,王昀,更·党木仁加甫..颅内血管外皮细胞瘤的治疗及预后影响因素分析[J].临床神经外科杂志,2018,15(3):218-222,5.
