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肥胖对精子发生机制影响的研究进展

牟珍妮 孙振高 宋景艳 刘红根 乔岩 夏庆昌

生殖医学杂志2018,Vol.27Issue(6):591-594,4.
生殖医学杂志2018,Vol.27Issue(6):591-594,4.DOI:10.3969/j.issn.1004-3845.2018.06.019

肥胖对精子发生机制影响的研究进展

Research progress on effect of obesity on spermatogenesis

牟珍妮 1孙振高 2宋景艳 3刘红根 1乔岩 3夏庆昌3

作者信息

  • 1. 山东中医药大学中医学院,济南 250014
  • 2. 山东中医药大学附属医院,济南 250014
  • 3. 山东中医药大学第一临床学院,济南 250014
  • 折叠

摘要

Abstract

The incidence rate of obesity in men has been rising in recent years.The effects of obesity on the semen quality have gradually attracted people's attention.However,the mechanism is complicated and still not clear yet.The mechanism which obesity affects spermatogenesis has been a research hotspot.Some studies found that obesity impacted semen quality and reduce male fertility mainly through affecting endocrine,inducing inflammatory response,increasing oxidative stress response etc.This review discusses and summarizes the relevant mechanisms in order to provide some guidance for clinical practice.

关键词

肥胖/精子获能/氧化应激/炎症反应/精子DNA损伤

Key words

Obesity/Sperm capacitation/Oxidative stress/Inflammation/Sperm DNA damage

引用本文复制引用

牟珍妮,孙振高,宋景艳,刘红根,乔岩,夏庆昌..肥胖对精子发生机制影响的研究进展[J].生殖医学杂志,2018,27(6):591-594,4.

基金项目

国家自然科学基金(81674018,81373676) (81674018,81373676)

生殖医学杂志

OACSTPCD

1004-3845

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