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中医药对肠道紧密连接蛋白调节作用的研究进展

常雄飞 赵鲁卿 贾梦迪 朱春洋 张声生

天津中医药2018,Vol.35Issue(6):472-476,5.
天津中医药2018,Vol.35Issue(6):472-476,5.DOI:10.11656/j.issn.1672-1519.2018.06.19

中医药对肠道紧密连接蛋白调节作用的研究进展

Advances in study of the effect of traditional Chinese medicine on the intestinal tight junction proteins

常雄飞 1赵鲁卿 2贾梦迪 1朱春洋 1张声生1

作者信息

  • 1. 首都医科大学附属北京中医医院消化中心,北京 100010
  • 2. 北京中医药大学,北京 100029
  • 折叠

摘要

Abstract

The intestinal mechanical barrier plays an important role in protection the body from infiltrating of toxic substances and the tight junction proteins were the structural basis, including claudin-1, occluidn and ZO-1 and so on. The intestinal mechanical barrier and tight junction proteins were closely related to many digestive diseases, such as ulcerative colitis, acute pancreatitis, irritable bowel syn-drome, functional dyspepsia. Recently many researches have found that the traditional Chinese medicine can modulate the intestinal tight junction proteins. This article reviewed the advances in study of the effect of traditional Chinese medicine on the intestinal tight junction proteins.

关键词

紧密连接蛋白/机械屏障/中医药

Key words

tight junction protein/mechanical barrier/traditional Chinese medicine

分类

医药卫生

引用本文复制引用

常雄飞,赵鲁卿,贾梦迪,朱春洋,张声生..中医药对肠道紧密连接蛋白调节作用的研究进展[J].天津中医药,2018,35(6):472-476,5.

基金项目

国家自然科学基金项目(8177150167) (8177150167)

国家自然科学基金项目(8150150319) (8150150319)

北京市医院管理局青苗计划(QML20161002). (QML20161002)

天津中医药

OACSTPCD

1672-1519

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