医疗卫生装备2018，Vol.39Issue(6)：24-28,42,6.DOI:10.7687/j.issn1003-8868.2018.06.024
不同频率rTMS对对侧运动区神经血管 变化及耦合关系影响研究
Influences of different frequencies of repetitive transcranial magnetic stimulation on neurovascular coupling in contralateral motor region
摘要
Abstract
Object To investigate the changes of neurovascular coupling (NVC) in the contralateral cerebral motor region under the action of repetitive transcranial magnetic stimulation (rTMS) at different frequencies. Methods Some experiments were designed, the electroencephalography (EEG) signals and the near-infrared spectra (NIRS) of the subjects were obtained under different rTMS stimulation frequencies, and EEG power spectrum of each frequency band and NIRS blood oxygen signals to the contralateral movement area were computed and the change characteristics and correlation were analyzed.Results For different stimulation frequencies, the energy of each frequency band of EEG increased after the stimulation, and then decreased rapidly. The oxyhemoglobin (HbO2) concentration was decreased during stimulation, and then raised. The change rate of the two signals varied with different stimulation frequencies, while the change trend was the same.The EEG power spectrum was negatively correlated with the change of HbO2 concentration after stimulation, and it had delayed effect in varying degrees in the period after stimulation.Conclusion The effect of rTMS on the coupling of nerves and vessels in the contralateral cerebral motor region can be reliably revealed by the study of EEG combined with NIRS. This study will be helpful to the development of effective RTMS treatment parameters, and the results are expected to be applied in clinical treatment.关键词
重复经颅磁刺激/神经血管耦合/脑电/近红外光谱/对侧运动区Key words
repetitive transcranial magnetic stimulation/neurovascular coupling/electroencephalography/near-infrared spectra/contralateral motor region分类
医药卫生引用本文复制引用
刘睿旭,靳静娜,王欣,周晓青,刘志朋,殷涛..不同频率rTMS对对侧运动区神经血管 变化及耦合关系影响研究[J].医疗卫生装备,2018,39(6):24-28,42,6.基金项目
国家重大科学仪器开发专项(2012YQ12004605) （2012YQ12004605）
天津市科技支撑重点项目(17YFZCSY00730) （17YFZCSY00730）
