首页|期刊导航|药物分析学报(英文)|Quantification and pharmacokinetic study of tumor-targeting agent MHI148-clorgyline amide in mouse plasma using liquid chromatography-electrospray ionization tandem mass spectrometry
药物分析学报(英文)2018,Vol.8Issue(3):153-159,7.
Quantification and pharmacokinetic study of tumor-targeting agent MHI148-clorgyline amide in mouse plasma using liquid chromatography-electrospray ionization tandem mass spectrometry
Quantification and pharmacokinetic study of tumor-targeting agent MHI148-clorgyline amide in mouse plasma using liquid chromatography-electrospray ionization tandem mass spectrometry
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MHI148-clorgyline/HPLC/Mass spectrometry/PharmacokineticsKey words
MHI148-clorgyline/HPLC/Mass spectrometry/Pharmacokinetics引用本文复制引用
Zhijun Wang,Bogdan Z. Olenyuk,Jean Chen Shih,Jeffrey Wang..Quantification and pharmacokinetic study of tumor-targeting agent MHI148-clorgyline amide in mouse plasma using liquid chromatography-electrospray ionization tandem mass spectrometry[J].药物分析学报(英文),2018,8(3):153-159,7.基金项目
This work was supported by USC-Taiwan Center for Transla-tional Research, the Daniel Tsai Family Fund and Boyd & Elsie Welin Professorship and by the Department of Defense Prostate Cancer Research Program Grant W81XWH-12-1-0282 (to J.C. Shih and B.Z. Olenyuk). We also thank Dr. Rajesh Kota, Dr. Ramin Dubey and Dr. Ivan V. Grishagin for help in synthesizing NMI-amide and precursors and Mr. Bin Qian for assistance in animal experiments (Department of Pharmacology and Pharma-ceutical Sciences, University of Southern California, Los Angeles, CA, USA). (to J.C. Shih and B.Z. Olenyuk)