中国美容医学2018，Vol.27Issue(5)：26-29,4.
微针导入氨甲环酸联合Q开关1064nm激光治疗黄褐斑疗效观察
Clinical Observation of Microneedle Importing Tranexamic Acid into Skin Combined with Q Switch 1064nm Laser for Treating Chloasma
孙慧 1吴志波 2倪小丽 1陈韡 1王大光2
作者信息
- 1. 南京医科大学附属友谊整形外科医院皮肤科 江苏 南京 210029
- 2. 南京医科大学第一附属医院皮肤科江苏 南京 210029
- 折叠
摘要
Abstract
Objective To investigate the clinical efficacy and adverse reactions of microneedle importing tranexamic acid into skin combined with Q Switch 1064nm laser to treat chloasma. Methods 94 patients with chloasma were randomly selected from department of dermatology in our hospital during April 2014 to April 2015, and these patients were divided into two groups: the control group was treated by only Q switch 1064nm laser, a total of 62 patients; the observation group were treated by combined method including microneedle importing tranexamic acid into skin for 4 times, and then used Q switch 1064nm laser treatment for 6 times,a total of 32 patients. The average area of melasma and severity index scores were calculated respectively before and after treatment. The adverse effects and patient satisfaction survey were recorded at the same time. Results The score of MASI in the observation group decreased from 13.58±3.39 to 8.79±1.69, and the effective rate was 96.88％,compared with the MASI score in the control group decreased from 13.89±3.23 to 10.74±1.92 and the effective rate was 81.25％, the observation group was significantly better than the control group. The adverse reactions in the observation group were significantly less than the control group, and the patient's satisfaction was higher in the observation group than in the control group. Conclusion Microneedle importing tranexamic acid into skin combined with Q Switch 1064nm is effective in the treatment of chloasma, and it has the value of popularization in clinic.关键词
微针/Q开关1064nm激光/黄褐斑/氨甲环酸/疗效Key words
microneedle/Q switch 1064nm laser/chloasma/tranexamic acid/curative effect分类
医药卫生引用本文复制引用
孙慧,吴志波,倪小丽,陈韡,王大光..微针导入氨甲环酸联合Q开关1064nm激光治疗黄褐斑疗效观察[J].中国美容医学,2018,27(5):26-29,4.
