中国循证儿科杂志2017，Vol.12Issue(1)：1-6,6.DOI:10.3969/j.issn.1673-5501.2017.01.001
孕前男性和夫妻双方共同补充叶酸的横断面调查及影响因素分析
A cross-sectional study on prevalence of paternal and parental preconception folic acid supplement use and its influencing factors
摘要
Abstract
Objective To investigate the prevalence and determinants of paternal preconception folic acid (FA) supplement use.Methods This study was based on cross-sectional data from sixteen maternity and child hospitals (centers) or general hospitals located in nine districts of Shanghai.Participants were enrolled from pre-pregnant physical examination clinics,aged 20-50 years.They conducted the questionnaire during the waiting time at waiting-room and restored it before they leaved.The questionnaire data entry was conducted with double times and logical test.Participants were categorized according to the use of FA or multivitamin (MV),the group had used FA or MV supplement was named users,in contrast,the group had not used FA or MV supplement was named nonusers.The correlation between the prevalence of FA supplement use and the selected socio demographic characteristics (age,education,occupation,household annual income,area of research site),lifestyle (smoking situation,drinking situation) Were analyzed.Variables were analyzed as determinants of FA intake using chi-square statistical test and multivariate Logistical regression,respectively.Results Overall,4 224 pregnancy planners were enrolled,4 122 participants were analyzed including 2 343 women and 1 881 men and 1 762 families.Average age was 30.5±4.3,94.5％ were highly educated families.The prevalence of preconception FA supplement use was 15.8％ (292/185) in man and 42.6％ in women.The prevalence of FA supplement use was higher among men with higher education and income,at traditional district,and with healthy lifestyle factors such as being a nonsmoker.Within 1762 families,223 were FA supplement user families,551 were nonuser families.The prevalence of parental FA supplement use was higher among families with higher education and income,living in traditional district,and in families with nonsmoker.Multivariate Logistical regression indicated paternal preconception FA supplement use was more likely among the population in traditional district (OR =8.60,95％ CI:6.12,12.07) and with their spouse using FA supplement (OR =1.44,95％ CI:1.08,1.93).Conclusion Prevalence of paternal and parental preconception FA supplement use are approximately one third of maternal FA supplement use.Maternal FA supplement use is far below the National Health and Family Planning Commission requirements,which indicates that education of folic acid supplement knowledge is deeply needed.关键词
男性/叶酸/孕前/出生缺陷Key words
Male/Folic acid/Preconception/Birth defects引用本文复制引用
王定美,张羿,叶莹,姜袁,马晓静,严卫丽,黄国英..孕前男性和夫妻双方共同补充叶酸的横断面调查及影响因素分析[J].中国循证儿科杂志,2017,12(1):1-6,6.基金项目
1国家重点研发计划重点专项项目:2016YFC1000500 （）
2上海市第四轮公共卫生三年行动计划项目:2015-82 （）
