摘要
Abstract
Objective To explore the effect of dietary intervention on autistic core symptoms, gastroin-testinal dysfunction, and allergy as well as other related symptoms in children with autism spectrum disorders ( ASD) . Methods A total of 47 ASD children were recruited in this study, with 32 in the dietary intervention group and 15 in the control group. Children in the dietary intervention group received behavior rehabilitation training and were restricted on intolerant food ( including gluten, eggs, milk, and other intolerant food as detected) for three months, while children in the control group only received behavior rehabilitation training. Childhood Autism Rating Scale ( CARS) , Clinical Language State Questionnaire ( CLSQ) and other symptom assessing questionnaires were used to assess the symptom alleviation after the 3-month intervention, including autistic core symptoms, gastrointestinal dysfunction, allergy, choosy in food dysfunction, agitation and sleep disorder. Results CARS scores were significantly lower (34. 4±6. 3 vs. 29. 3±5. 2) and CLSQ expression and cognition scores were significantly higher (4. 2±3. 0 vs. 6. 8±2. 9, 5. 7±2. 4 vs. 7. 4±1. 9) in children in the dietary intervention group, while no statistically significant difference was observed in these scores in the control group. Additionally, as compared to the control group, children in the dietary intervention group showed better improvement in gastrointestinal dysfunction, agitation, and choosy in food. Alleviation of allergy and sleep disorder was not different between these two groups. Conclusion Restricting intolerant food intake could alleviate the core symptoms of ASD and other related symptoms such as gastrointestinal dysfunction, agitation, and choosy in food in ASD children.关键词
孤独症谱系障碍/食物不耐受/饮食/疗效Key words
Autism spectrum disorder/Food intolerance/Diet/Effect
