中华临床免疫和变态反应杂志2018，Vol.12Issue(2)：204-208,5.DOI:10.3969∕j.issn.1673-8705.2018.02.013
菌群代谢产物与变态反应性疾病
Metabolites of microbiome in allergic diseases
摘要
Abstract
In recent decades, the incidence of allergic diseases has increased markedly. It was shown that abnormal microbiome was involved in the occurrence and development of allergic diseases by results of accumulating studies. There are more than 1000 bacterial species colonized in the human gut. Now it is known that gut microbiome can produce different metabolites from dietary materials. These metabolites and bacterial components influence the regulation of host immune responses, resulted in affecting the development of various immunological diseases, including allergic disease. The recent findings regarding these microbial metabolites in the regulation of allergic diseases were primarily summarize in this review.关键词
菌群/代谢产物/变态反应/短链脂肪酸/长链脂肪酸/氨基酸/维生素Key words
Microbiome/Metabolites/Allergic diseases/Short-chain fatty acid/Long-chain fatty acid/Amino acid/Vitamin引用本文复制引用
徐蓓蕾,姚煦..菌群代谢产物与变态反应性疾病[J].中华临床免疫和变态反应杂志,2018,12(2):204-208,5.基金项目
中国医学科学院医学与健康科技创新工程(2016-12M-1-005) （2016-12M-1-005）
国家自然科学基金(81371735、81573045) （81371735、81573045）
江苏省自然科学基金(BK20150166) CAMS Innovation Fund for Medical Sciences(2016-12M-1-005) （BK20150166）
National Natural Science Foundation of China(81371735, 81573045) （81371735, 81573045）
Natural Science Foundation of Jiangsu Province(BK20150166) （BK20150166）
