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信号传导及转录激活因子信号通路在自然杀伤细胞研究中的进展

于淮海 孙雨飞 金昌洙 付强

转化医学杂志2018,Vol.7Issue(3):188-193,6.
转化医学杂志2018,Vol.7Issue(3):188-193,6.DOI:10.3969/j.issn.2095-3097.2018.03.016

信号传导及转录激活因子信号通路在自然杀伤细胞研究中的进展

Research progress of signal transducers and activators of transcription signal pathway in natural killer cell

于淮海 1孙雨飞 1金昌洙 1付强1

作者信息

  • 1. 264003 山东 烟台,滨州医学院
  • 折叠

摘要

Abstract

Natural killer ( NK) cells play a critical role in anti-tumor immunity, anti-infec-tion immunity and reproductive immunity. The study of its signaling pathway is helpful for us to bet-ter understand the biological behavior of NK cells. Signal transducers and activators of transcription ( STAT) signaling pathway is one of the most studied pathways in recent years which plays an impor-tant role in the growth, development and functional regulation of NK cells. In this paper, we re-viewed the recent progress of STAT signaling pathway in NK cells to promote the application of NK cell in translational medicine.

关键词

自然杀伤细胞/信号传导及转录激活因子信号通路/肿瘤免疫/感染免疫/生殖免疫

Key words

Natural killer ( NK ) cell/Signal transducers and activators of transcription ( STAT) signal pathway/Tumor immunology/Infection immunology/Reproductive immunology

分类

医药卫生

引用本文复制引用

于淮海,孙雨飞,金昌洙,付强..信号传导及转录激活因子信号通路在自然杀伤细胞研究中的进展[J].转化医学杂志,2018,7(3):188-193,6.

基金项目

国家自然科学基金面上项目(81370730,81571512) (81370730,81571512)

山东省自然科学基金重点项目(ZR2015JL027) (ZR2015JL027)

山东省高等学校优秀中青年骨干教师国际合作培养计划资助 ()

转化医学杂志

OACSTPCD

2095-3097

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