中国现代中药2017，Vol.19Issue(8)：1187-1192,6.DOI:10.13313/j.issn.1673-4890.2017.8.027
不同粒径黄芪超微粉理化性质的研究
Physicochemical Properties of Different Particle Diameters of Ultrafine Powder of Astragali Radix
邓雯 1杨泽锐 2程翔燕 3成金乐1
作者信息
- 1. 国家中医药管理局中药破壁饮片技术与应用重点研究室,广东 中山528437
- 2. 广东省破壁粉粒工程技术研究开发中心,广东 中山528437
- 3. 中山市中智药业集团有限公司,广东 中山 528437
- 折叠
摘要
Abstract
Objective:This article is aimed to analyze and compare the differences of physicochemical properties in different particle diameters of Astragali Radix ultrafine powders in order to provide guidance for clinical application.Methods:Different particle diameters of ultrafine powders were produced by using jet mill.Then their powder characteristics such as particle diameters,powder morphology,liquidity,hygroscopicity and dissolution behavior of active ingredients were investigated.Results:With the decreasing of particle diameters of Astragali Radix ultrafine powder,both the specific surface area and the moisture increased while the liquidity and yield decreased slightly.Also,the dissolution rates and the concentrations of the active ingredients increased overall.Conclusion:An appropriate degree of superfine grinding can promote the dissolution of active ingredients of Astragali Radix,but a smaller particle diameters will lead to a lower yield,which is Impractical for production.Therefor,a comprehensive survey is needed for the choice of the best particle diameters in production.关键词
黄芪/超微粉/不同粒径/理化性质/溶出度Key words
Astragali Radix/ultrafine granular powder/physicochemical properties/different particle diameters/dissolution behavior引用本文复制引用
邓雯,杨泽锐,程翔燕,成金乐..不同粒径黄芪超微粉理化性质的研究[J].中国现代中药,2017,19(8):1187-1192,6.
