摘要
Abstract
Objective To investigate the relationship between pregnant women's serum pregnancy related protein (PAPP-A),insulin resistance index (IR) and gestational diabetes (GDM).Methods A total of 89 GDM patients in the hospital were selected as study group,60 normal pregnant women were as control group,fasting plasma glucose (FPG),2 h plasma glucose (2 h PG),fasting insulin (FINS),2 h plasma insulin (PINS),IR,insulin and insulin secretion (IS) index and serum PAPP-A were measured,relationship between serum PAPP-A,IR and blood glucose index were analyzed.Results The study group had higher FPG,and IR,and lower FINS,PINS,PAPP-A,and IS than the control group (P ＜ 0.05).Serum PAPP-A showed a negative correlation with IR (r =-0.562,P ＜0.05),and a positive correlation with IS (r =0.491,P ＜0.05),a negative correlation with FPG,and a positive correlation with FINS;and IR was positively correlated with FPG,and negatively correlated with FINS.Conclusion Serum PAPP-A and IR index of GDM pregnant women are significantly higher,the higher the index is,the higher the level of blood glucose and the lower the insulin secretion ability.关键词
妊娠相关蛋白/胰岛素抵抗指数/妊娠期糖尿病Key words
pregnant-related protein/insulin resistance index/gestational diabetes分类
医药卫生
