临床肝胆病杂志2018，Vol.34Issue(6)：1147-1151,5.DOI:10.3969/j.issn.1001-5256.2018.06.001
药物性肝损伤的研究进展及我国存在的问题
Research advances in drug-induced liver injury and existing problems in China
陈成伟1
作者信息
- 1. 上海南京军区临床肝病研究中心,上海200035
- 折叠
摘要
Abstract
At present, Drug -induced liver injury(DILI) has become the most common cause of acute liver injury in clinical practice .This article elaborates on the pathogenesis of DILI , new biomarkers, liver tolerance to drug toxicity, adaptability and susceptibility, and testing threshold of alanine aminotransferase .Meanwhile, we should understand the development history of diagnostic scale , develop unified standards and understanding, and attach importance to DILI induced by medicinal herbs and dietary supplements , and in -depth studies on the pathogenesis of DILI should be performed to prevent or reduce DILI .There are several problems in DILI studies in China and obvious gaps between China and foreign countries, with a lack of basic research and blanks in clinical aspects .Therefore, we must strive to keep up with international research so that drugs can better serve the human .关键词
药物性肝损伤/述评Key words
drug -induced liver injury/editorial分类
医药卫生引用本文复制引用
陈成伟..药物性肝损伤的研究进展及我国存在的问题[J].临床肝胆病杂志,2018,34(6):1147-1151,5.
