临床肝胆病杂志2018，Vol.34Issue(6)：1166-1168,3.DOI:10.3969/j.issn.1001-5256.2018.06.005
加强基于大数据的药物性肝损伤的科学研究和监管
Strengthening the scientific research and supervision of drug-induced liver injury based on big data
摘要
Abstract
Drug -induced liver injury (DILI) is one of the most important drug -induced diseases and has complex clinical phenotypes ,which leads to its unpredictability.The involvement of many types of drugs and complex population heterogeneity pose great challenges to the supervision of scientific research on DILI.Most of our knowledge of DILI comes from the international databases of long -term follow -up.However, there are still many unmet clinical needs in the field of DILI .Strengthening the scientific research on drug -induced liver injury based on big data helps us to understand DILI better and it is the premise for scientific supervision .关键词
药物性肝损伤/数据库Key words
drug -induced liver injury/database分类
医药卫生引用本文复制引用
茅益民..加强基于大数据的药物性肝损伤的科学研究和监管[J].临床肝胆病杂志,2018,34(6):1166-1168,3.基金项目
"十三五"科技重大专项(2017ZX09304016) （2017ZX09304016）
国家自然科学基金课题(81670524) （81670524）
